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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKD1
All Species:
27.27
Human Site:
T422
Identified Species:
60
UniProt:
Q15139
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15139
NP_002733.2
912
101704
T422
H
T
K
R
K
S
S
T
V
M
K
E
G
W
M
Chimpanzee
Pan troglodytes
XP_001170806
912
101668
T422
H
T
K
R
K
S
S
T
V
M
K
E
G
W
M
Rhesus Macaque
Macaca mulatta
XP_001114639
912
101836
T422
H
T
K
R
K
S
S
T
V
M
K
E
G
W
M
Dog
Lupus familis
XP_851386
884
99023
T394
H
T
K
R
K
S
S
T
V
L
K
E
G
W
M
Cat
Felis silvestris
Mouse
Mus musculus
Q62101
918
102049
T428
H
T
K
R
R
S
S
T
V
M
K
E
G
W
M
Rat
Rattus norvegicus
Q9WTQ1
918
102025
T428
H
T
K
R
R
S
S
T
V
M
K
E
G
W
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512992
948
106688
T458
H
T
K
R
K
S
S
T
V
M
K
E
G
W
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685219
878
98838
N386
H
T
K
R
K
S
S
N
V
M
K
E
G
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61267
476
54243
L45
K
N
I
K
I
K
S
L
G
T
S
S
K
Y
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45818
1070
120565
K624
Q
T
K
R
K
N
N
K
L
L
K
E
G
W
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39009
513
58614
L82
T
F
H
A
E
F
H
L
L
Q
M
D
V
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
92
N.A.
92.5
93.1
N.A.
81.3
N.A.
N.A.
80.1
N.A.
20.1
N.A.
43.7
N.A.
Protein Similarity:
100
99.5
99.3
93.9
N.A.
95
95.4
N.A.
86.3
N.A.
N.A.
86.7
N.A.
32
N.A.
56.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
N.A.
N.A.
86.6
N.A.
6.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
20
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
82
0
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
82
0
0
% G
% His:
73
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
82
10
64
10
0
10
0
0
82
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
19
19
19
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
64
10
0
0
0
64
% M
% Asn:
0
10
0
0
0
10
10
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
82
19
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
73
82
0
0
0
10
10
0
0
0
% S
% Thr:
10
82
0
0
0
0
0
64
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
73
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
82
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _